Have you followed the instructions for virgin-tv-error-codes/v53 ? Error code V53 is often due to a local outage/fault, or cable connections, especially the white coaxial cable which should be tight and secure.
Check the service status at the top of the page. You can also a run a test on your equipment from there.
If nothing is showing you could also try the Service Status number 0800 561 0061. This often gives details of more local issues down to postcode level.
The picture at the bottom of this post shows the other channels on the same mux as CH5 HD. If you have access to those channels and the same issues occur then it's probably a signal fault and you'll likely need an engineer visit.
If the other channels are unaffected then it's more than likely a box fault which will need replacing.
Whichever way, you will need to contact the Faults team on 150 from a Virgin landline, or 0345 454 1111, options 1,1 and 2 (Faults) but best to call at 8am, or mid afternoon tea time to avoid call queues
When calling Faults hopefully the system will recognise that you've used the online faults checker and place you into a queue for an agent to pick up.
If not and you get the automated response asking you to press 1 for the link to online support, ignore the options and don't press any buttons then you should be placed into a queue and an agent should pick up the phone and resolve the problem.

Dave
The Service you do for others is the rent you pay for your room here on Earth - Muhammad AliI don't work for Virgin Media.
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