On a desktop / laptop device try opening a Command Shell or Terminal window and enter the following where username:password is replaced with your email address and password, i.e. richard.branson@virginmedia.com:Y54kpX5g:
curl -v smtps://smtp.virginmedia.com -u username:password
Do not post the resulting output here but instead review it for possible reported causes for not being able to send and then post just the redacted part here or the VM error code.
In the meantime use webmail to send emails, https://mail2.virginmedia.com
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